DNA test - CSNB
Congenital stationary night blindness
Details about the disease
CSNB is an inherited, degenerative disease caused by a defect in the gene RPE65, which encodes a protein that plays a crucial role in vision.
The clinical effects include night blindness and a loss of vision in daylight that can vary between individual dogs. This disease manifests in Briard dogs from a young age (from 6 weeks-of-age onwards).
How it is inherited
The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.
For advice on how to breed from your DNA tested dog, why not visit our information guide www.thekennelclub.org.uk/download/14960/breedingdna.pdf